INDICATIONS AND USAGE

Approval: 2003INDICATIONS AND USAGECIALIS® is a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of:erectile dysfunction (ED) (1.1)the signs and symptoms of benign prostatic hyperplasia (BPH) (1.2)ED and the signs and symptoms of BPH (ED/BPH) (1.3)If CIALIS is used with finasteride to initiate BPH treatment, such use is recommended for up to 26 weeks (1.4).DOSAGE AND ADMINISTRATION CIALIS for use as needed: ED: Starting dose: 10 mg as needed prior to sexual activity.

• Research and development continue beyond the original Cialis patent.
• Studies have investigated tadalafil for other conditions like Raynaud's.
• Its use in pulmonary hypertension is approved under the name Adcirca.
• Research into new formulations or delivery methods is ongoing.
• The understanding of PDE5 inhibitors' long-term effects continues to evolve.
• Lilly and other companies invest in next-generation erectile dysfunction treatments.
• The legacy of Cialis has shaped the entire ED treatment landscape.

Increase to 20 mg or decrease to 5 mg based upon efficacy/tolerability.

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

It should never be relied upon for specific medical advice. If you have any questions or concerns, please talk to your doctor. If you are a consumer or patient please visit this version. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights cialis drug cost do not include all the information needed to use CIALIS safely and effectively. See full prescribing information for CIALIS.CIALIS (tadalafil) tablets, for oral useInitial U.S. Improves erectile function compared to placebo up to 36 hours post dose. Not to be taken more than once per day (2.1).CIALIS for once daily use:CIALIS may be taken without regard to food (2.5).DOSAGE FORMS AND STRENGTHSTablets: 5 mg, 10 mg, 20 mg (3).CONTRAINDICATIONSAdministration of CIALIS to patients using any form of organic nitrate is contraindicated. CIALIS was shown to potentiate the hypotensive effect of nitrates (4.1).History of known serious hypersensitivity reaction to CIALIS or ADCIRCA® (4.2).Administration with guanylate cyclase (GC) stimulators, such as riociguat (4.3).WARNINGS AND PRECAUTIONSPatients should not use CIALIS if sex is inadvisable due to cardiovascular status (5.1).Use of CIALIS with alpha-blockers, antihypertensives or substantial amounts of alcohol (≥5 units) may lead to hypotension (5.6, 5.9).CIALIS is not recommended in combination with alpha-blockers for the treatment of BPH because efficacy of the combination has not been adequately studied and because of the risk of blood pressure lowering. Caution is advised when CIALIS is used as a treatment for ED in men taking alpha-blockers.

Product	Dosage	Quantity + Bonus	Price
Cialis Generic	40mg	60 + 6 Pills	130.98€ 124.74€	Buy
Cialis Generic	20mg	270 + 10 Pills	335.21€ 319.25€	Buy
Cialis Soft Tabs	20mg	120 + 6 Pills	248.64€ 236.80€	Buy
Cialis Generic	5mg	90 + 6 Pills	115.91€ 110.39€	Buy
Cialis Original	20mg	8 Pills	61.70€ 58.76€	Buy
Cialis Generic	20mg	120 + 8 Pills	188.15€ 179.19€	Buy
Cialis Professional	20mg	20 Pills	78.33€ 74.60€	Buy
Cialis Generic	40mg	20 Pills	59.47€ 56.64€	Buy
Cialis Generic	5mg	270 + 10 Pills	205.81€ 196.01€	Buy
Cialis Professional	40mg	30 Pills	148.94€ 141.85€	Buy
Cialis Generic	20mg	60 + 6 Pills	117.76€ 112.15€	Buy
Cialis Original	20mg	64 + 4 Pills	274.18€ 261.12€	Buy

(2.7, 5.6, 7.1, 12.2)Patients should seek emergency treatment if an erection lasts >4 hours. Use CIALIS with caution in patients predisposed to priapism (5.3).Patients should stop CIALIS and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non-arteritic anterior ischemic optic neuropathy (NAION).

8.7 Renal Impairment

Over 80% of men find them effective as treatments for their ED, and there is no observed difference between the two pills in trials. Cialis might have been the first-ever “weekend pill” but it is no longer the only option in town for the same results. Tadalafil also keeps pace with Cialis when it comes to how long you need to wait for it to kick in. Both start from about half an hour after you take them, which means no long delays before you get down to business. The bioequivalence between Tadalafil and Cialis also means that you should expect them to work best in the same circumstances.

Are they approved by the FDA (Food and Drug Administration)?

You can achieve the best results if you are able to relax and get into the mood. The medicine only builds on your own natural sexual arousal; it’s not a magic pill — so the more aroused you are through sexual stimulation, the better the medication will work. This type of medication has been through extensive trials and has been available on prescription for decades. Whether you go for branded Cialis or unbranded Tadalafil, they are safe and suitable for use, and they are both licensed for erectile dysfunction treatment. The most common side effects of Tadalafil are mild, including symptoms like a headache, stuffy nose (nasal congestion), low blood pressure, indigestion, dizziness, or slight facial flushing.

TUFTS Clinical Trial Material Round Table

But even these mild side effects are rare. In even rarer cases, there have been more serious side effects reported, including back pain, chest pain and priapism. Note: If you experience sudden vision loss or symptoms akin to a heart attack, contact your doctor immediately and refrain from further sexual activity. There are possible drug interactions with other prescription drugs for antibiotics, antifungals, antidepressants, high blood pressure, and some other drugs for medical conditions. If you’re in doubt about whether you should take Cialis or Tadalafil, contact a medical professional at Manual.As a responsible patient, it’s crucial that if you’ve been warned against taking Cialis, you should also avoid Tadalafil. CIALIS should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION.

Active Ingredient	Dosage (mg)	Added Ingredients	Formulation Type
Tadalafil	20	L-arginine, Ginseng	Tablet
Tadalafil	10	Maca root, Zinc	Capsule
Sildenafil	50	Bioperine, Rhodiola	Sachet
Vardenafil	20	L-citrulline	Tablet

Patients with a "crowded" optic disc may also be at an increased risk of NAION (5.4, 6.2).Patients should stop CIALIS and seek prompt medical attention in the event of sudden decrease or loss of hearing (5.5).Prior to initiating treatment with CIALIS for BPH, consideration should be given to other urological conditions that may cause similar symptoms (5.14).ADVERSE REACTIONSMost common adverse reactions (≥2%) include headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, and pain in limb (6.1).To report SUSPECTED ADVERSE REACTIONS, contact Eli Lilly and Company at 1-800-LillyRx (1-800-545-5979) or FDA at 1-800-FDA-1088 or INTERACTIONSCIALIS can potentiate the hypotensive effects of nitrates, alpha-blockers, antihypertensives or alcohol (7.1).CYP3A4 inhibitors (e.g. ketoconazole, ritonavir) increase CIALIS exposure (2.7, 5.10, 7.2) requiring dose adjustment: CIALIS for use as needed: no more than 10 mg every 72 hoursCIALIS for once daily use: dose not to exceed 2.5 mgCYP3A4 inducers (e.g. rifampin) decrease CIALIS exposure (7.2).USE IN SPECIFIC POPULATIONSHepatic Impairment (2.6, 5.8, 8.6):Mild or Moderate: Dosage adjustment may be needed.Severe: Use is not recommended.Renal Impairment (2.6, 5.7, 8.7):Patients with creatinine clearance 30 to 50 mL/min: Dosage adjustment may be needed.Patients with creatinine clearance less than 30 mL/min or on hemodialysis: For use as needed: Dose should not exceed 5 mg every 72 hours. Once daily use is not recommended.See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.Revised: 3/2026 CIALIS® is a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of: the signs and symptoms of benign prostatic hyperplasia (BPH) (1.2) ED and the signs and symptoms of BPH (ED/BPH) (1.3) If CIALIS is used with finasteride to initiate BPH treatment, such use is recommended for up to 26 weeks (1.4).

8.5 Geriatric Use

Over a weekend away, that would mean potentially as little as 30 minutes of waiting time for a stronger erection. As opposed to at least twice that on daily medicine. Among the non-pharmaceutical measures are a lot of good common sense ideas that are great to combine with some medical support. As we’ve outlined in other articles, taking care of yourself with a balanced diet and getting enough rest and exercise can only help you in the battle against ED. They will also give medicines like Tadalafil a strong base to build upon.

Erectile Dysfunction

You may have heard of the Cialis brand first, but that doesn’t mean it should necessarily be your first port of call. For those of you who are looking for a medication you can simply take and forget about for the weekend, Tadalafil offers this benefit for the most competitive price. Order from a reputable and accredited supplier, and follow the advice in the medication leaflet. Each individual is different, but now you can be sure that Tadalafil and Cialis are medical equivalents. While we've ensured that everything you read on the Health Centre is medically reviewed and approved, information presented here is not intended to be a substitute for professional medical advice, diagnosis, or treatment. CIALIS for use as needed: ED: Starting dose: 10 mg as needed prior to sexual activity. Not to be taken more than once per day (2.1).

• Overdose symptoms may include severe headache, nausea, and dizziness.
• Priapism (a painful, prolonged erection) is a medical emergency.
• If an erection lasts more than 4 hours, seek immediate medical help.
• Standard supportive care is used for overdose; dialysis is not effective.
• Contact a poison control center or emergency room immediately.
• Have the medication container or label available for identification.
• Never take extra doses to increase the effect.

ED: Starting dose: 10 mg as needed prior to sexual activity.

14.2 CIALIS for Once Daily Use for ED

Any side effects you had with Cialis would be repeated with the Tadalafil, because they’re not just the same class of drugs – they have an identical active ingredient. Well, Cialis comes in a more attractive package; it has motivational slogans printed on the pill sleeve; the pill has been manufactured so that it’s shaped in a special way. And if the overall appearance of a product matters to you, or you tend to feel a strong emotional attachment to a brand, then that might be a good enough reason to consider Cialis over Tadalafil. Otherwise, you’ll find far greater value opting for the generic version. They are all approved for treatment of erectile dysfunction.

What is Cialis (tadalafil)? How does tadalafil work?

All of these Phosphodiesterase 5 inhibitors work in a similar way: the relaxation of the penile blood vessels to support expansion, which gives a stronger erection during arousal. What varies between them is the dosage, bioavailability, the length of time their effect takes to kick in, the amount of time they last for, and the side effect profiles. The main benefit of Tadalafil is how long it can last — up to 36 hours, as opposed to the roughly 4-6 hours for Sildenafil or Viagra. It also has the most variable possible dosage, making it quite a versatile treatment. A lower dose could super cialis be taken every day, for example.

APhA Academy of Student Pharmacists (APhA-ASP)

Avanafil and Spedra kick in a little quicker, making them suitable for “on-demand” use shortly prior to anticipated sexual intercourse. But they also don’t last as long as Tadalafil — which is a major drawback for some men. Vardenafil (Levitra) and Sildenafil both have the downside of being effective for less time than Tadalafil. That said, they work well and if you’re looking for something for less than 36 hours, they’re good options for most men. Tadalafil also takes the same amount of time to take effect as some shorter-acting options, but it provides support for much longer. CIALIS may be taken without regard to food (2.5). Administration of CIALIS to patients using any form of organic nitrate is contraindicated.

• Patient assistance programs were offered by Lilly for those who qualified.
• The Lilly Cialis Value Program provided savings on prescription costs.
• Programs were designed for uninsured or underinsured patients in the US.
• Eligibility was based on income and insurance status.
• Similar patient support programs exist in other countries.
• With generics available, out-of-pocket costs have decreased overall.
• Patients should consult their doctor or pharmacist for current options.

CIALIS was shown to potentiate the hypotensive effect of nitrates (4.1).